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Article

Structure-function study of a heptad repeat positioned near the transmembrane domain of Sendai virus fusion protein which blocks virus-cell fusion.

The Journal of biological chemistry - 16 Oct 1998

Ghosh J K, Peisajovich S G, Ovadia M, Shai Y

Abstract excerpt

A synthetic heptad repeat, SV-473, derived from Sendai virus fusion protein is a potent inhibitor of virus-cell fusion. In order to understand the mechanism of the inhibitory effect, we synthesized and fluorescently labeled SV-465, an extended version of SV-473 by one more heptad, its mutant pept...

Topics

Amino Acid Sequence
Energy Transfer
Hemolysis
Humans
Liposomes
Membrane Fusion
Membrane Proteins
Molecular Sequence Data
Mutation
Peptide Fragments
Phospholipids
Protein Structure, Secondary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Repetitive Sequences, Amino Acid

Respirovirus

Spectroscopy, Fourier Transform Infrared

Viral Fusion Proteins

Virus Replication

Source

Identifiers

PMID: 9765238
DOI: 10.1074/jbc.273.42.27182

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9765238-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Structure-function study of a heptad repeat positioned near the transmembrane domain of Sendai virus fusion protein which blocks virus-cell fusion.PMID 9765238Read ↗

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