Article
Why are two different cross-linkers necessary for actin bundle formation in vivo and what does each cross-link contribute?
The Journal of cell biology - 5 Oct 1998
Tilney L G, Connelly P S, Vranich K A, Shaw M K, Guild G M
Abstract excerpt
In developing Drosophila bristles two species of cross-linker, the forked proteins and fascin, connect adjacent actin filaments into bundles. Bundles form in three phases: (a) tiny bundles appear; (b) these bundles aggregate into larger bundles; and (c) the filaments become maximally cross-linked...
Topics
- Actins
- Animals
- Animals, Genetically Modified
- Carrier Proteins
- Chromosomes
- Cross-Linking Reagents
- Drosophila melanogaster
- Female
- Larva
- Male
- Microfilament Proteins
- Microscopy, Electron
- Microscopy, Electron, Scanning
- Mutation
- Pupa
- Sensory Receptor Cells