Article
Proper cellular reorganization during Drosophila spermatid individualization depends on actin structures composed of two domains, bundles and meshwork, that are differentially regulated and have different functions.
Molecular biology of the cell - 1 Jun 2008
Noguchi Tatsuhiko, Lenartowska Marta, Rogat Aaron D, Frank Deborah J, Miller Kathryn G
Abstract excerpt
During spermatid individualization in Drosophila, actin structures (cones) mediate cellular remodeling that separates the syncytial spermatids into individual cells. These actin cones are composed of two structural domains, a front meshwork and a rear region of parallel bundles. We show here that the two domains form separately in time, are regulated by different sets of actin-associated proteins, can be formed...
Topics
- Actin Cytoskeleton
- Actin-Related Protein 2-3 Complex
- Actins
- Animals
- Drosophila melanogaster
- Male
- Mutation
- Profilins
- Protein Transport
- Spermatids