Linkage disequilibrium and linkage analysis of the glucose-6-phosphatase gene.

doi:10.1007/s004390050807

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Article

Linkage disequilibrium and linkage analysis of the glucose-6-phosphatase gene.

Human genetics - 1 Aug 1998

Wong L J, Liang M H, Hwu W L, Lam C W

Abstract excerpt

Recent studies have indicated that the four most common mutations account for 78% of mutant alleles in the glucose-6-phosphatase (G6Pase) gene. A significant fraction of mutant alleles remain unidentified. Thus, informative polymorphic markers are necessary for linkage analysis in carrier testing...

Topics

Female
Genetic Linkage
Glucose-6-Phosphatase
Glycogen Storage Disease Type I
Humans
Linkage Disequilibrium
Male
Mutation
Pedigree

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