Article
No evidence of the inactivating mutation (C566T) in the follicle-stimulating hormone receptor gene in Brazilian women with premature ovarian failure.
Fertility and sterility - 1 Sept 1998
da Fonte Kohek M B, Batista M C, Russell A J, Vass K, Giacaglia L R, Mendonca B B, Latronico A C
Abstract excerpt
OBJECTIVE: To investigate the presence of FSH receptor gene mutations in women with premature ovarian failure (POF). DESIGN: Clinical and molecular studies. SETTING: Research laboratory in a university setting. PATIENT(S): Fifteen 46,XX women with POF and 42 normal fertile controls. INTERVENTION(S): Exon 7 was amplified and digested with BsmI to screen for the previously described inactivating mutation C566T....
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