The Finnish follicle-stimulating hormone receptor gene mutation is rare in North American women with 46,XX ovarian failure.

doi:10.1016/s0015-0282(97)00480-9

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Article

The Finnish follicle-stimulating hormone receptor gene mutation is rare in North American women with 46,XX ovarian failure.

Fertility and sterility - 1 Feb 1998

Layman L C, Amde S, Cohen D P, Jin M, Xie J

Abstract excerpt

OBJECTIVE: To determine whether FSH receptor gene missense mutation in Finnish women with premature ovarian failure (POF) is present in North American women with POF. DESIGN: Analysis of DNA from patients and controls. PATIENT(S): Thirty-five women with POF and ten normal controls. INTERVENTION(S...

Topics

Adolescent
Adult
Alleles
DNA
Diploidy
Electrophoresis, Polyacrylamide Gel
Ethnicity
Female
Finland
Humans
North America
Point Mutation
Polymerase Chain Reaction
Primary Ovarian Insufficiency
Receptors, FSH

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