Article
Serologic and nucleotide sequencing analyses of a novel DR52-associated DRB1 allele with the DR 'NJ25' specificity, designated DRB1*1307.
Human immunology - 1 Oct 1994
Kaneshige T, Hashimoto M, Matsumoto Y, Kinoshita T, Hirasawa T, Uchida K, Inoko H
Abstract excerpt
A novel DR52-associated DRB1* allele, designated DRB1*1307, was encountered in the course of our HLA-DRB1 genotyping study in a Japanese population by PCR-RFLP. Comparison of the nucleotide sequence of its second exon with those of the other known DRB1 alleles revealed that DRB1*1307 was most sim...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- HLA-DR Antigens
- HLA-DRB1 Chains
- Humans
- Japan
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length