Article
Centromeric protein B null mice are viable with no apparent abnormalities.
Developmental biology - 15 Sept 1998
Perez-Castro A V, Shamanski F L, Meneses J J, Lovato T L, Vogel K G, Moyzis R K, Pedersen R
Abstract excerpt
The centromere protein B (CENP-B) is a centromeric DNA/binding protein. It recognizes a 17-bp sequence motif called the CENP-B box, which is found in the centromeric region of most chromosomes. It binds DNA through its amino terminus and dimerizes through its carboxy terminus. CENP-B protein has been proposed to perform a vital role in organizing chromatin structures at centromeres. However, other evidence does...
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