Article
Centromeric protein B null mice are viable with no apparent abnormalities.
Developmental biology - 15 Sept 1998
Perez-Castro A V, Shamanski F L, Meneses J J, Lovato T L, Vogel K G, Moyzis R K, Pedersen R
Abstract excerpt
The centromere protein B (CENP-B) is a centromeric DNA/binding protein. It recognizes a 17-bp sequence motif called the CENP-B box, which is found in the centromeric region of most chromosomes. It binds DNA through its amino terminus and dimerizes through its carboxy terminus. CENP-B protein has...
Topics
- Animals
- Autoantigens
- Cell Line
- Centromere Protein B
- Chromosomal Proteins, Non-Histone
- Crosses, Genetic
- DNA-Binding Proteins
- Fertility
- Fetal Viability
- Genotype
- Histocytochemistry
- Immunohistochemistry
- Litter Size
- Male
- Mice
- Mice, Knockout
- Microtubules
- RNA, Messenger