Article
Truncation and heme pocket mutations reduce production of functional catalase HPII in Escherichia coli.
Protein engineering - 1 Jul 1998
Sevinc M S, Switala J, Bravo J, Fita I, Loewen P C
Abstract excerpt
The subunit of catalase HPII from Escherichia coli is 753 residues in length and contains a core of approximately 500 residues, with high structural similarity to all other heme catalases. To this core are added extensions of approximately 80 and 180 residues at the N- and C-termini, respectively...
Topics
- Catalase
- Escherichia coli
- Mutation
- Protein Folding
- Structure-Activity Relationship