Article
Absence of the fragile X CGG trinucleotide repeat expansion in girls diagnosed with a pervasive developmental disorder.
The Journal of pediatrics - 1 Sept 1998
Meyer G A, Blum N J, Hitchcock W, Fortina P
Abstract excerpt
The purpose of this study was to determine the prevalence of the fragile X (FRAX) CGG trinucleotide expansion in a population of young girls (n = 45) diagnosed with pervasive developmental disorder (PDD). Their mean age was 43.7 months (range, 25 to 132 months). Diagnoses included autistic disord...
Topics
- Autistic Disorder
- Blotting, Southern
- Child
- Child, Preschool
- Cohort Studies
- Confidence Intervals
- Cytosine
- DNA
- Female
- Fragile X Mental Retardation Protein
- Fragile X Syndrome
- Guanine
- Humans
- Intellectual Disability
- Mutation
- Nerve Tissue Proteins
- Prevalence
- Prospective Studies