Article
A PCR-based test suitable for screening for fragile X syndrome among mentally retarded males.
Human genetics - 1 Jun 1996
Haddad L A, Mingroni-Netto R C, Vianna-Morgante A M, Pena S D
Abstract excerpt
Ever since the identification of the genetic cause of fragile X syndrome as the expansion of an unstable trinucleotide sequence, several diagnostic strategies have evolved from molecular studies. However, we still lack a simple test suitable for population screening. We have therefore developed a nonisotopic polymerase chain reaction (PCR)-based technique for the identification of fragile X full mutations among...
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