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Article

Molecular aspects of ovarian cancer.

Best practice & research. Clinical obstetrics & gynaecology - 1 Aug 2002

Wenham Robert M, Lancaster Johnathan M, Berchuck Andrew

Abstract excerpt

Ovarian cancer is caused by genetic alterations that disrupt proliferation, apoptosis, senescence and DNA repair. Approximately 10% of ovarian cancers arise in women who have inherited mutations in cancer susceptibility genes (BRCA1 or BRCA2). The ability to perform genetic testing allows identification of women at increased risk who can be offered prophylactic oophorectomy or other interventions aimed at...

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Share to BRCA1 gene
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Share to Genes, Tumor Suppressor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cell Transformation, Neoplastic

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Source

Identifiers

PMID: 12413930
DOI: 10.1053/beog.2002.0298

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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