Article
[Development of gentamicin-resistant Small Colony Variants of S. aureus after implantation of gentamicin chains in osteomyelitis as a possible cause of recurrence].
Zeitschrift fur Orthopadie und ihre Grenzgebiete - 1 Jan 2000
von Eiff C, Lindner N, Proctor R A, Winkelmann W, Peters G
Abstract excerpt
AIM: Recently, S. aureus small colony variants (SCVs) were reported to persist within cultured endothelial cells and to cause persistent and antibiotic resistant infections in humans. Because gentamicin can very reproducably select for electron transport deficient SCVs as shown in earlier in vitr...
Topics
- Adult
- Bacterial Proteins
- Chronic Disease
- Drug Resistance, Microbial
- Endonucleases
- Female
- Genetic Variation
- Gentamicins
- Humans
- Methylmethacrylates
- Microbial Sensitivity Tests
- Micrococcal Nuclease
- Osteomyelitis
- Recurrence
- Staphylococcal Infections
- Staphylococcus aureus