Article
Clinical and molecular characteristics of infections with CO2-dependent small-colony variants of Staphylococcus aureus.
Journal of clinical microbiology - 1 Aug 2010
Gómez-González Carmen, Acosta Joshi, Villa Jennifer, Barrado Laura, Sanz Francisca, Orellana M Angeles, Otero Joaquín R, Chaves Fernando
Abstract excerpt
Most Staphylococcus aureus small-colony variants (SCVs) are auxotrophs for menadione, hemin, or thymidine but rarely for CO(2). We conducted a prospective investigation of all clinical cases of CO(2)-dependent S. aureus during a 3-year period. We found 14 CO(2)-dependent isolates of S. aureus from 14 patients that fulfilled all requirements to be considered SCVs, 9 of which were methicillin resistant. The...
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