3'-blocking damage of DNA as a mutagenic lesion caused by hydrogen peroxide in Escherichia coli.

doi:10.1269/jrr.39.137

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Article

3'-blocking damage of DNA as a mutagenic lesion caused by hydrogen peroxide in Escherichia coli.

Journal of radiation research - 1 Jun 1998

Takemoto T, Zhang Q M, Matsumoto Y, Mito S, Izumi T, Ikehata H, Yonei S

Abstract excerpt

Ionizing radiation and hydrogen peroxide (H2O2) produce many types of oxidative DNA damage such as strand breaks, apurinic/apyrimidinic (AP) sites, base modifications and 3'-blocking damage such as 3'-phosphoglycolated and 3'-phosphorylated termini. AP sites and 3'-blocking damage are repairable...

Topics

DNA Damage
Escherichia coli
Hydrogen Peroxide
Mutation

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