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Article

Gene defect behind APECED: a new clue to autoimmunity.

Human molecular genetics - 1 Jan 1998

Björses P, Aaltonen J, Horelli-Kuitunen N, Yaspo M L, Peltonen L

Abstract excerpt

The molecular background of human autoimmunity is poorly understood. Although many autoimmune diseases have a genetic basis, the actual disease appearance results from a complex interplay between genes and environment and thus these diseases represent typical multifactorial diseases. Even with molecular tools provided by the Human Genome Project, it still remains a challenge to identify the predisposing DNA...

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Source

Identifiers

PMID: 9735375
DOI: 10.1093/hmg/7.10.1547

Genes

AIRE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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APECED: A Paradigm of Complex Interactions between Genetic Background and Susceptibility FactorsSemantic proximity Read ↗

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