Article
Gene defect behind APECED: a new clue to autoimmunity.
Human molecular genetics - 1 Jan 1998
Björses P, Aaltonen J, Horelli-Kuitunen N, Yaspo M L, Peltonen L
Abstract excerpt
The molecular background of human autoimmunity is poorly understood. Although many autoimmune diseases have a genetic basis, the actual disease appearance results from a complex interplay between genes and environment and thus these diseases represent typical multifactorial diseases. Even with mo...
Topics
- Animals
- Autoimmunity
- Cloning, Molecular
- Humans
- In Situ Hybridization, Fluorescence
- Mice
- Models, Genetic
- Mutation
- Phenotype
- Polyendocrinopathies, Autoimmune
- Transcription Factors
- AIRE Protein