Article
Characterization of nebulette and nebulin and emerging concepts of their roles for vertebrate Z-discs.
Journal of molecular biology - 11 Sept 1998
Millevoi S, Trombitas K, Kolmerer B, Kostin S, Schaper J, Pelin K, Granzier H, Labeit S
Abstract excerpt
Nebulin is an 800 kDa large actin-binding protein specific to skeletal muscle and thought to act as a molecular template that regulates the length of thin filaments. Recently, a 100 kDa nebulin-like protein has been described in the avian cardiac muscle and referred to as nebulette. We have deter...
Topics
- Actin Cytoskeleton
- Amino Acid Sequence
- Carrier Proteins
- Chromosome Mapping
- Chromosomes, Human, Pair 10
- Chromosomes, Human, Pair 2
- Cloning, Molecular
- Cytoskeletal Proteins
- Genetic Variation
- Humans
- LIM Domain Proteins
- Molecular Sequence Data
- Muscle Proteins
- Muscle, Skeletal