Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cbfa1 in bone development.

Current opinion in genetics & development - 1 Aug 1998

Komori T, Kishimoto T

Abstract excerpt

A factor fundamental to bone formation has been identified. Gene targeting shows that core-binding factor alpha 1 (Cbfa1) plays an essential role in bone formation and osteoblast differentiation. Thus, it is now possible to begin examining the molecular mechanism of bone formation--especially osteoblast differentiation.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Development
Share to Cell Differentiation
Share to Gene Expression

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Neoplasm Proteins

Share to Osteoblasts

Share to Transcription Factors

Source

Identifiers

PMID: 9729728
DOI: 10.1016/s0959-437x(98)80123-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cbfa1 in bone development.PMID 9729728Read ↗

Role of Cbfa1 in osteoblast differentiation and functionSemantic proximity Read ↗

A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development.Semantic proximity Read ↗

CBFA1: A molecular switch in osteoblast biologySemantic proximity Read ↗

Cbfa1, a Candidate Gene for Cleidocranial Dysplasia Syndrome, Is Essential for Osteoblast Differentiation and Bone DevelopmentSemantic proximity Read ↗

[Cbfa1/Runx2, an essential transcription factor for the regulation of osteoblast differentiation].Semantic proximity Read ↗

Discovery: Osf2/Cbfa1, a master gene of bone formation.Semantic proximity Read ↗

Osf2/Cbfa1: A Transcriptional Activator of Osteoblast DifferentiationSemantic proximity Read ↗

Cbfβ: A key regulator in skeletal stem cell differentiation, bone development, and diseaseSemantic proximity Read ↗

Functions of AP1 (Fos/Jun) in bone developmentSemantic proximity Read ↗

Deletion of core-binding factor β (Cbfβ) in mesenchymal progenitor cells provides new insights into Cbfβ/Runxs complex function in cartilage and bone developmentSemantic proximity Read ↗

Runx2/Cbfa1: A Multifunctional Regulator of Bone FormationSemantic proximity Read ↗

Core binding factor and its role in normal hematopoietic developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.