Genomic imprinting, development and disease—is pre-eclampsia caused by a maternally imprinted gene?

Abstract excerpt

Several genes in conserved clusters are expressed from only the maternal or the paternal allele. The other allele has been genetically silenced ('imprinted') by its passage through one sex. Many known imprinted genes have effects on embryonic or trophoblast growth or fetal development, and mutation or loss of the single active copy causes diseases such as Prader-Willi, Angelmann and Beckwith-Wiederman syndromes....

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