Article
The gene for death agonist BID maps to the region of human 22q11.2 duplicated in cat eye syndrome chromosomes and to mouse chromosome 6.
Genomics - 1 Aug 1998
Footz T K, Birren B, Minoshima S, Asakawa S, Shimizu N, Riazi M A, McDermid H E
Abstract excerpt
Cat eye syndrome (CES) is associated with a duplication of a segment of human chromosome 22q11.2. Only one gene, ATP6E, has been previously mapped to this duplicated region. We now report the mapping of the human homologue of the apoptotic agonist Bid to human chromosome 22 near locus D22S57 in t...
Topics
- Animals
- Apoptosis
- BH3 Interacting Domain Death Agonist Protein
- Carrier Proteins
- Chromosome Breakage
- Chromosome Mapping
- Chromosomes, Human, Pair 22
- Cloning, Molecular
- Eye Diseases
- Gene Dosage
- Genetic Markers
- Humans
- Intellectual Disability
- Mice
- Molecular Sequence Data
- Multigene Family
- Phenotype
- RNA, Messenger