Article
Relative binding affinities of OmpR and OmpR-phosphate at the ompF and ompC regulatory sites.
Journal of molecular biology - 4 Sept 1998
Head C G, Tardy A, Kenney L J
Abstract excerpt
In Escherichia coli, porin gene expression is regulated, in part, by the two-component regulatory system consisting of the two proteins EnvZ and OmpR. EnvZ is an integral inner membrane protein that is phosphorylated by cytoplasmic ATP on a histidine residue. EnvZ modulates the activity of OmpR by phosphorylation and dephosphorylation. Phospho-OmpR (OmpR-P) binds to the porin genes ompF and ompC to regulate their...
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