Association of the FcepsilonRIbeta gene with bronchial hyper-responsiveness in an Italian population.

doi:10.1136/jmg.35.8.680

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Article

Association of the FcepsilonRIbeta gene with bronchial hyper-responsiveness in an Italian population.

Journal of medical genetics - 1 Aug 1998

Trabetti E, Cusin V, Malerba G, Martinati L C, Casartelli A, Boner A L, Pignatti P F

Abstract excerpt

A study of two DNA polymorphisms (i2 RsaI, E237G) in the gene for the beta subunit of the IgE high affinity receptor (FcepsilonRIbeta) was performed in 168 Italian families with atopic asthmatic children. The prevalence of the E237G allele in the Italian population was 4%, so this polymorphism wa...

Topics

Alleles
Asthma
Child
Deoxyribonucleases, Type II Site-Specific
Female
Humans
Italy
Male
Pedigree
Polymorphism, Genetic
Receptors, IgE

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