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Article

Differential effects of EGF receptor signalling on neuroblast lineages along the dorsoventral axis of the Drosophila CNS.

Development (Cambridge, England) - 1 Sept 1998

Udolph G, Urban J, Rüsing G, Lüer K, Technau G M

Abstract excerpt

The Drosophila ventral nerve cord derives from a stereotype population of about 30 neural stem cells, the neuroblasts, per hemineuromere. Previous experiments provided indications for inductive signals at ventral sites of the neuroectoderm that confer neuroblast identities. Using cell lineage analysis, molecular markers and cell transplantation, we show here that EGF receptor signalling plays an instructive role...

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Identifiers

PMID: 9693133
DOI: 10.1242/dev.125.17.3291

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Differential effects of EGF receptor signalling on neuroblast lineages along the dorsoventral axis of the Drosophila CNS.PMID 9693133Read ↗

The Drosophila EGF receptor controls the formation and specification of neuroblasts along the dorsal-ventral axis of the Drosophila embryo.Semantic proximity Read ↗

Genetic control of dorsoventral patterning and neuroblast specification in the Drosophila Central Nervous System.Semantic proximity Read ↗

Interaction between Drosophila EGF receptor and vnd determines three dorsoventral domains of the neuroectoderm.Semantic proximity Read ↗

Role of the Drosophila EGF receptor in determination of the dorsoventral domains of escargot expression during primary neurogenesis.Semantic proximity Read ↗

Commitment of CNS progenitors along the dorsoventral axis of Drosophila neuroectoderm.Semantic proximity Read ↗

Formation and specification of ventral neuroblasts is controlled by vnd in Drosophila neurogenesis.Semantic proximity Read ↗

Molecular and genetic intimations of the function of Delta, and EGF-like gene required for ectodermal differentiation in Drosophila.Semantic proximity Read ↗

The glycosyltransferase Fringe promotes Delta-Notch signaling between neurons and glia, and is required for subtype-specific glial gene expression.Semantic proximity Read ↗

Notch regulates the switch from symmetric to asymmetric neural stem cell division in the Drosophila optic lobe.Semantic proximity Read ↗

The CNS midline cells control the spitz class and Egfr signaling genes to establish the proper cell fate of the Drosophila ventral neuroectoderm.Semantic proximity Read ↗

Regulation of post-embryonic neuroblasts by Drosophila Grainyhead.Semantic proximity Read ↗

Developmental control by the Drosophila EGF receptor homolog DER.Semantic proximity Read ↗

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