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Article

Mitochondrial dysfunction in neurodegenerative disorders.

Biochimica et biophysica acta - 10 Aug 1998

Schapira A H

Abstract excerpt

Mutations of mitochondrial DNA (mtDNA) are associated with a wide spectrum of disorders encompassing the myopathies, encephalopathies and cardiomyopathies, in addition to organ specific presentations such as diabetes mellitus and deafness. The pathogenesis of mtDNA mutations is not fully understood although it is assumed that their final common pathway involves impaired oxidative phosphorylation. The...

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PMID: 9714816
DOI: 10.1016/s0005-2728(98)00115-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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