Article
Mitochondrial dysfunction in neurodegenerative diseases.
Neurochemical research - 1 Dec 2008
Schapira Anthony H V
Abstract excerpt
Mitochondria play a pivotal role in mammalian cell metabolism, hosting a number of important biochemical pathways including oxidative phosphorylation. As might be expected from this fundamental contribution to cell function, abnormalities of mitochondrial metabolism are a common cause of human disease. Primary mutations of mitochondrial DNA result in a diverse group of disorders often collectively referred to as...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.