Cloning of a novel member of the low-density lipoprotein receptor family.

doi:10.1016/s0378-1119(98)00311-4

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Article

Cloning of a novel member of the low-density lipoprotein receptor family.

Gene - 17 Aug 1998

Hey P J, Twells R C, Phillips M S, Yusuke Nakagawa, Brown S D, Kawaguchi Y, Cox R, Guochun Xie, Dugan V, Hammond H, Metzker M L, Todd J A, Hess J F

Abstract excerpt

A gene encoding a novel transmembrane protein was identified by DNA sequence analysis within the insulin-dependent diabetes mellitus (IDDM) locus IDDM4 on chromosome 11q13. Based on its chromosomal position, this gene is a candidate for conferring susceptibility to diabetes. The gene, termed low-...

Topics

Amino Acid Sequence
Animals
Chromosomes, Human, Pair 11
Cloning, Molecular
Cosmids
DNA
DNA, Bacterial
DNA, Complementary
Diabetes Mellitus, Type 1
Gene Expression
Genetic Predisposition to Disease
Genomic Library
Humans
LDL-Receptor Related Proteins

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Low Density Lipoprotein Receptor-Related Protein-5

Membrane Proteins

Mice

Microsatellite Repeats

Source

Open in PubMed

Identifiers

PMID: 9714764
DOI: 10.1016/s0378-1119(98)00311-4

Genes

LDLR
LRP5
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9714764-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.