Yellow fever 17D vaccine virus isolated from healthy vaccinees accumulates very few mutations.

doi:10.1016/s0168-1702(98)00036-7

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Yellow fever 17D vaccine virus isolated from healthy vaccinees accumulates very few mutations.

Virus research - 1 May 1998

Xie H, Cass A R, Barrett A D

Abstract excerpt

The live attenuated yellow fever (YF) vaccine strain 17D is one of the safest vaccines in use today with only 22 cases of reversion to virulence documented from over 300 million doses administered. We have isolated virus in cell culture from sera of six volunteers who received 17D vaccine and fou...

Topics

Amino Acid Sequence
Amino Acid Substitution
Animals
Chlorocebus aethiops
Genetic Variation
Humans
Molecular Sequence Data
Mutation
Point Mutation
Polymerase Chain Reaction
Sequence Alignment
Sequence Analysis, DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Homology, Amino Acid

Vaccines, Attenuated

Vero Cells

Viral Nonstructural Proteins

Viral Vaccines

Yellow fever virus

Source

Open in PubMed

Identifiers

PMID: 9712515
DOI: 10.1016/s0168-1702(98)00036-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9712515-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Yellow fever 17D vaccine virus isolated from healthy vaccinees accumulates very few mutations.PMID 9712515Read ↗

The phylogeny of yellow fever virus 17D vaccines.Semantic proximity Read ↗

Molecular analysis of yellow fever virus 17DD vaccine strain.Semantic proximity Read ↗

Molecular characterization of the 17D-204 yellow fever vaccine.Semantic proximity Read ↗

Hepatitis and death following vaccination with 17D-204 yellow fever vaccine.Semantic proximity Read ↗

Complete nucleotide sequence of yellow fever virus vaccine strains 17DD and 17D-213Semantic proximity Read ↗

E Protein Domain III Determinants of Yellow Fever Virus 17D Vaccine Strain Enhance Binding to Glycosaminoglycans, Impede Virus Spread, and Attenuate VirulenceSemantic proximity Read ↗

Characterization of a viscerotropic yellow fever vaccine variant from a patient in Brazil.Semantic proximity Read ↗

Two mutations in NS2B are responsible for attenuation of the yellow fever virus (YFV) vaccine strain 17D.Semantic proximity Read ↗

Phenotypic and molecular analyses of yellow fever 17DD vaccine viruses associated with serious adverse events in Brazil.Semantic proximity Read ↗

Genetic variability among yellow fever virus 17D substrains.Semantic proximity Read ↗

The yellow fever 17D virus as a platform for new live attenuated vaccinesSemantic proximity Read ↗

Comparison of the live attenuated yellow fever vaccine 17D-204 strain to its virulent parental strain Asibi by deep sequencing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.