Article
Frequency of MAGE-3 gene expression in HLA-A2 positive patients with non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 May 1998
Gotoh K, Yatabe Y, Sugiura T, Takagi K, Ogawa M, Takahashi T, Takahashi T, Mitsudomi T
Abstract excerpt
Melanoma tumor antigens, MAGE-1 and -3 are presented on HLA-A1 and -Cw*1601, or -A1 and -A2, respectively, to the corresponding cytotoxic T lymphocytes (CTL). If CTL recognizing these antigens were generated in patients, clones of positive tumor cells should be eliminated. To ascertain whether such an immunological response is active in patients with lung cancer and to determine what fraction of lung cancer...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.