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Article

Expression of mage genes by non‐small‐cell lung carcinomas

15 Mar 1994

Abstract excerpt

Human gene MAGE-I codes for an antigen that is recognized on melanoma cells by autologous cytolytic T lymphocytes (CTL). This antigen is potentially useful as a target for cancer immunotherapy because gene MAGE-I is not expressed in any normal tissues except the testis. We tested 46 surgical samples of non-small-cell lung carcinomas and observed MAGE-I expression in 16 of them (35%). Genes MAGE-2 and 3, which are...

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Identifiers

PMID: 8119772
DOI: 10.1002/ijc.2910560612

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