Article
Variations in the vitamin D-binding protein (Gc locus) are associated with oral glucose tolerance in nondiabetic Pima Indians.
The Journal of clinical endocrinology and metabolism - 1 Aug 1998
Baier L J, Dobberfuhl A M, Pratley R E, Hanson R L, Bogardus C
Abstract excerpt
Electrophoretic variants of the vitamin D-binding protein (DBP) have been associated with type 2 diabetes as well as with metabolic characteristics that predispose to type 2 diabetes in several populations. The Gc gene that encodes DBP maps to chromosome 4q12, a region that has recently been found to be potentially linked to plasma glucose and insulin concentrations in Pima Indians. Therefore, the gene that...
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