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Article

Variations in the vitamin D-binding protein (Gc locus) are associated with oral glucose tolerance in nondiabetic Pima Indians.

The Journal of clinical endocrinology and metabolism - 1 Aug 1998

Baier L J, Dobberfuhl A M, Pratley R E, Hanson R L, Bogardus C

Abstract excerpt

Electrophoretic variants of the vitamin D-binding protein (DBP) have been associated with type 2 diabetes as well as with metabolic characteristics that predispose to type 2 diabetes in several populations. The Gc gene that encodes DBP maps to chromosome 4q12, a region that has recently been foun...

Topics

Adult
Alleles
Blood Glucose
Chromosomes, Human, Pair 4
Diabetes Mellitus, Type 2
Female
Gene Frequency
Genetic Variation
Glucose Tolerance Test
Humans
Indians, North American
Insulin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Polymorphism, Genetic

Prediabetic State

Vitamin D-Binding Protein

Source

Identifiers

PMID: 9709981
DOI: 10.1210/jcem.83.8.5043

Genes

DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9709981-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Variations in the vitamin D-binding protein (Gc locus) are associated with oral glucose tolerance in nondiabetic Pima Indians.PMID 9709981Read ↗

Variations in the vitamin D-binding protein (Gc locus) and risk of type 2 diabetes mellitus in French Caucasians.Semantic proximity Read ↗

Variations in vitamin D-binding protein (group-specific component protein) are associated with fasting plasma insulin levels in Japanese with normal glucose tolerance.Semantic proximity Read ↗

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Reduced serum vitamin D-binding protein levels are associated with type 1 diabetes.Semantic proximity Read ↗

The DBP Phenotype Gc-1f/Gc-1f Is Associated with Reduced Risk of Cancer. The Tromsø Study.Semantic proximity Read ↗

Association of vitamin D and vitamin D binding protein (DBP) gene polymorphism with susceptibility of type 2 diabetes mellitus in Bangladesh.Semantic proximity Read ↗

Characterization of additional vitamin D binding protein variants.Semantic proximity Read ↗

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Prevalence of vitamin D deficiency in women from southern Brazil and association with vitamin D-binding protein levels and GC-DBP gene polymorphisms.Semantic proximity Read ↗

Common variants of the vitamin D binding protein gene and adverse health outcomes.Semantic proximity Read ↗

Vitamin D binding protein gene and genetic susceptibility to type 2 diabetes mellitus in a Polish population.Semantic proximity Read ↗

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