Article
Association of an X-chromosome dodecamer insertional variant allele with mental retardation.
Molecular psychiatry - 1 Jul 1998
Philibert R A, King B H, Winfield S, Cook E H, Lee Y H, Stubblefield B, Damschroder-Williams P, Dea C, Palotie A, Tengstrom C, Martin B M, Ginns E I
Abstract excerpt
Mental retardation is a prominent feature of many neurodevelopmental syndromes. In an attempt to identify genetic components of these illnesses, we isolated and sequenced a large number of human genomic cosmid inserts containing large trinucleotide repeats. One of these cosmids, Cos-4, maps to th...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- California
- Chromosome Mapping
- Conserved Sequence
- Cosmids
- DNA Transposable Elements
- Europe
- Exons
- Female
- Finland
- Fragile X Syndrome
- Gene Library
- Genetic Variation