Article
The aberrant positioning of nuclei and the microtubular cytoskeleton in Saccharomyces cerevisiae due to improper actin function.
Microbiology (Reading, England) - 1 Jul 1998
Kopecká Marie, Gabriel Miroslav
Abstract excerpt
An excentric position of the nuclei, random orientation of mitoses, and multinuclear budding cells were identified in part of a population of temperature-sensitive (ts) Saccharomyces cerevisiae actin mutants at the permissive temperature of 23 degrees C by fluorescence and electron microscopy. The phenotype resembled that of mutants in beta-tubulin, dynein, JNM1, NUM1, ACT3, ACT5, myosins, profilin, tropomyosin...
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