Inhibition of ribozymes by deoxyribonucleotides and the origin of DNA.

doi:10.1007/pl00006368

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Article

Inhibition of ribozymes by deoxyribonucleotides and the origin of DNA.

Journal of molecular evolution - 1 Aug 1998

León P E

Abstract excerpt

Two catalytic functions were required, minimally, for the appearance of DNA in evolution: a ribonucleotide reductase (RNR) and a reverse transcriptase (RT). If one accepts the explanatory strength of the RNA world model, it is clear that DNA molecules arose in the RNA world at some stage during t...

Topics

DNA
DNA-Directed RNA Polymerases
Deoxyribonucleotides
Evolution, Molecular
Models, Theoretical
Mutation
RNA, Catalytic
RNA-Directed DNA Polymerase
Ribonucleotide Reductases

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