The impact of HLA on long-term outcome after thymectomy for myasthenia gravis.

doi:10.1016/s0165-5728(98)00120-9

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Article

The impact of HLA on long-term outcome after thymectomy for myasthenia gravis.

Journal of neuroimmunology - 1 Aug 1998

Machens A, Löliger C, Pichlmeier U, Emskötter T, Busch C, Izbicki J R

Abstract excerpt

In a retrospective series of 86 patients with myasthenia gravis, the only factors predictive of improvement in muscular strength after transsternal thymectomy were preoperative severity of myasthenia (90% versus 54%, p = 0.0014) and HLA-B8 (79% versus 50%, p = 0.0060) in bivariable and multivaria...

Topics

Alleles
HLA-B8 Antigen
Haplotypes
Humans
Myasthenia Gravis
Prognosis
Regression Analysis
Retrospective Studies
Severity of Illness Index
Thymectomy
Treatment Outcome

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