Epigenetics and epimutagens: some new perspectives on cancer, germ line effects and endocrine disrupters.

doi:10.1016/s0027-5107(98)00046-3

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Article

Epigenetics and epimutagens: some new perspectives on cancer, germ line effects and endocrine disrupters.

Mutation research - 25 May 1998

MacPhee D G

Abstract excerpt

It is known that a variety of chemicals, including certain base analogues and reactive oxygen species, can alter the phenotypes of mammalian cells epigenetically, i.e., without changing their DNA sequence information in any way. The implications of such findings are not trivial, but do not seem t...

Topics

Animals
Endocrine System
Environmental Pollutants
Gene Expression Regulation
Germ Cells
Humans
Mutagenesis
Neoplasms
Phenotype

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