Epigenetics and epimutagens: some new perspectives on cancer, germ line effects and endocrine disrupters.

Abstract excerpt

It is known that a variety of chemicals, including certain base analogues and reactive oxygen species, can alter the phenotypes of mammalian cells epigenetically, i.e., without changing their DNA sequence information in any way. The implications of such findings are not trivial, but do not seem to have been the focus of a great deal of attention amongst mutation researchers to date. In part this may be a...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Environmental Pollutants
• Share to Gene Expression Regulation
• Share to Germ Cells