Article
Escherichia coli strains lacking protein HU are UV sensitive due to a role for HU in homologous recombination.
Journal of bacteriology - 1 Aug 1998
Li S, Waters R
Abstract excerpt
hupA and hupB encode the alpha and beta subunits of the Escherichia coli histone-like protein HU. Here we show that E. coli hup mutants are sensitive to UV in the rec+ sbc+, recBC sbcA, recBC sbcBC, umuDC, recF, and recD backgrounds. However, hupAB mutations do not enhance the UV sensitivity of resolvase-deficient recG ruvA strains. hupAB uvrA and hupAB recG strains are supersensitive to UV. hup mutations enhance...
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