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Article

Escherichia coli strains lacking protein HU are UV sensitive due to a role for HU in homologous recombination.

Journal of bacteriology - 1 Aug 1998

Li S, Waters R

Abstract excerpt

hupA and hupB encode the alpha and beta subunits of the Escherichia coli histone-like protein HU. Here we show that E. coli hup mutants are sensitive to UV in the rec+ sbc+, recBC sbcA, recBC sbcBC, umuDC, recF, and recD backgrounds. However, hupAB mutations do not enhance the UV sensitivity of r...

Topics

Bacterial Outer Membrane Proteins
Bacterial Proteins
Carrier Proteins
DNA-Binding Proteins
Dose-Response Relationship, Radiation
Escherichia coli
Escherichia coli Proteins
Genetic Markers
Genotype
Mutation
Novobiocin
Recombination, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topoisomerase II Inhibitors

Ultraviolet Rays

Source

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Identifiers

PMID: 9683467
DOI: 10.1128/JB.180.15.3750-3756.1998
PMCID: PMC107354

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9683467-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Escherichia coli strains lacking protein HU are UV sensitive due to a role for HU in homologous recombination.PMID 9683467Read ↗

Histone-like protein HU is required for recA gene-dependent DNA repair and SOS induction pathways in UV-irradiated Escherichia coli.Semantic proximity Read ↗

Escherichia coli HU protein suppresses DNA-gyrase-mediated illegitimate recombination and SOS induction.Semantic proximity Read ↗

Increased sensitivity to gamma irradiation in bacteria lacking protein HU.Semantic proximity Read ↗

Loss of lambda prophage recombinogenicity in UV-irradiated Escherichia coli: the role of host genes ruvA, ruvB, ruvC, and recG.Semantic proximity Read ↗

HU-1 mutants of Escherichia coli deficient in DNA binding.Semantic proximity Read ↗

The RuvABC resolvase is indispensable for recombinational repair in sbcB15 mutants of Escherichia coli.Semantic proximity Read ↗

Involvement of RecF pathway recombination genes in postreplication repair in UV-irradiated Escherichia coli cells.Semantic proximity Read ↗

Abortive recombination in Escherichia coli ruv mutants blocks chromosome partitioning.Semantic proximity Read ↗

The RecU Holliday junction resolvase acts at early stages of homologous recombination.Semantic proximity Read ↗

UvrD helicase, unlike Rep helicase, dismantles RecA nucleoprotein filaments in Escherichia coli.Semantic proximity Read ↗

Modulation of DNA damage tolerance in Escherichia coli recG and ruv strains by mutations affecting PriB, the ribosome and RNA polymerase.Semantic proximity Read ↗

Recombination is essential for viability of an Escherichia coli dam (DNA adenine methyltransferase) mutant.Semantic proximity Read ↗

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