Article
Regulatory role of ALA-S and ALA-D in a haem-deficient mutant of Saccharomyces cerevisiae.
Cellular and molecular biology (Noisy-le-Grand, France) - 1 Jun 1998
Araujo L S, Lombardo M E, Del C Batlle A M
Abstract excerpt
The biochemical characteristics of a haem-deficient mutant strain B231 of Saccharomyces cerevisiae isolated from D273-10B strain are described. B231 strain accumulates substantial amounts of 5-aminolevulinic acid (ALA) and uroporphyrin III (uro III). This pattern of porphyrins accumulation is due to both a defect in uroporphyrinogen decarboxylase (Uro-D) activity and an enhancement of porphobilinogenase (PBGase)...
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