Article
Molecular cloning of a novel transcriptional repressor protein of the rat type 1 vasoactive intestinal peptide receptor gene.
The Journal of biological chemistry - 31 Jul 1998
Pei L
Abstract excerpt
This study demonstrates that the transcriptional repressor sequence of the rat vasoactive intestinal peptide receptor (VIPR) gene constitutes a 42-base pair core element that is the binding site for a nuclear protein. We showed that this element was able to confer transcriptional repression to a...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- COS Cells
- Cloning, Molecular
- DNA-Binding Proteins
- Gene Expression Regulation
- Genes, Reporter
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Promoter Regions, Genetic
- RNA, Messenger
- Rats
- Receptors, Vasoactive Intestinal Peptide
- Replication Protein C
- Repressor Proteins
- Sequence Alignment