Article
F5 Q506 mutation and the low prevalence of cardiovascular disease in Canadian Inuit.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Jun 1998
Mandelcorn R, Connelly P W, Boright A, Young T K, Hegele R A
Abstract excerpt
BACKGROUND: The Keewatin Inuit have a very low age-adjusted mortality rate from vascular diseases compared to the general population of Canada. Interethnic differences in both genetic and lifestyle factors have been offered as explanations for this observation. We previously found that compared to white subjects, the Inuit had a significantly increased prevalence of 4 candidate alleles for atherosclerosis-related...
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