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Article

Are Canadian Inuit at increased genetic risk for coronary heart disease?

Journal of molecular medicine (Berlin, Germany) - 1 May 1997

Hegele R A, Young T K, Connelly P W

Abstract excerpt

The Keewatin Inuit of the Northwest Territories of Canada have a very low age-adjusted mortality rate from coronary heart disease. We hypothesized that this apparent protection from disease has a genetic basis. We determined the prevalence of the disease-associated alleles of five candidate genes for atherosclerosis-related phenotypes. Surprisingly, four of the five alleles studied, namely AGT T235, FABP2 T54,...

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Source

Identifiers

PMID: 9181478
DOI: 10.1007/s001090050122

Genes

APOE
FABP2
AGT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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