Article
Chemokine receptors and the clinical course of HIV-1 infection.
Trends in microbiology - 1 Jun 1998
de Roda Husman A M, Schuitemaker H
Abstract excerpt
For several years, the cellular basis behind the differences in HIV-1 tropism and the species specificity of HIV-1 has remained unclear. Since the discovery that chemokine receptors are essential cofactors for entry of HIV-1 into cells, tremendous progress has been made in the understanding of the role played by co-receptors in HIV-1 biological variability, HIV-1 transmission and AIDS pathogenesis.
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.