Paget's disease of bone.

Abstract excerpt

Paget's disease of bone is a localized disorder of bone remodeling. Increased numbers of larger than normal osteoclasts initiate the process at affected skeletal sites, and the increase in bone resorption is followed by an increase in new bone formation, altering bone architecture. The signs and symptoms of Paget's disease are varied, depending in part on the location of the involved sites and the degree of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bone Density
• Share to Chromosomes, Human, Pair 18
• Share to Genetic Predisposition to Disease