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Functional Identification of Conjugation and Replication Regions of the Tetracycline Resistance Plasmid pCW3 fromClostridium perfringens

20 Jun 2006

Abstract excerpt

Clostridium perfringens causes fatal human infections, such as gas gangrene, as well as gastrointestinal diseases in both humans and animals. Detailed molecular analysis of the tetracycline resistance plasmid pCW3 from C. perfringens has shown that it represents the prototype of a unique family of conjugative antibiotic resistance and virulence plasmids. We have identified the pCW3 replication region by deletion...

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PMID: 16788202
DOI: 10.1128/jb.00298-06

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