Article
Osmotin, a plant antifungal protein, subverts signal transduction to enhance fungal cell susceptibility.
Molecular cell - 1 May 1998
Yun D J, Ibeas J I, Lee H, Coca M A, Narasimhan M L, Uesono Y, Hasegawa P M, Pardo J M, Bressan R A
Abstract excerpt
The plant pathogenesis-related protein osmotin is an antifungal cytotoxic agent that causes rapid cell death in the yeast S. cerevisiae. We show here that osmotin uses a signal transduction pathway to weaken defensive cell wall barriers and increase its cytotoxic efficacy. The pathway activated by osmotin includes the regulatory elements of the mating pheromone response STE4, STE18, STE20, STE5, STE11, STE7,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.