Overexpression of an unstable intrinsic factor-cobalamin receptor in Imerslund-Gräsbeck syndrome.

doi:10.1016/s0016-5085(98)70379-8

Back to search

Article

Overexpression of an unstable intrinsic factor-cobalamin receptor in Imerslund-Gräsbeck syndrome.

Gastroenterology - 1 Jul 1998

Eaton D M, Livingston J H, Seetharam B, Puntis J W

Abstract excerpt

Two sisters with Imerslund-Gräsbeck syndrome who presented with clinical features of cobalamin deficiency are described. Intrinsic factor-cobalamin receptor (IFCR) activity and protein levels were determined in ileal biopsy specimens by using radioisotope assay and immunoblotting, respectively. I...

Topics

Child
Female
Humans
Ileum
Malabsorption Syndromes
Phenotype
Receptors, Cell Surface
Vitamin B 12
Vitamin B 12 Deficiency

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.