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Article

ras mutation and platinum resistance in human ovarian carcinomas in vitro.

International journal of cancer - 3 Jul 1998

Holford J, Rogers P, Kelland L R

Abstract excerpt

A panel of 16 human ovarian carcinoma cell lines comprising cisplatin naive as well as those with acquired cisplatin resistance was studied to determine if there was a relationship between ras status and cisplatin sensitivity. From the ras expression studies alongside data produced by direct DNA sequencing, there was very little to suggest that ras overexpression or mutation plays a role in the cisplatin...

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Share to Carcinoma
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9639399
DOI: 10.1002/(sici)1097-0215(19980703)77:1<94::aid-ijc15>3.0.co;2-9

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Source receipt: pubmed, retrieved 7 Sept 2026.

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