Article
Frequency and carrier risk associated with common BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer patients.
American journal of human genetics - 1 Jul 1998
Fodor F H, Weston A, Bleiweiss I J, McCurdy L D, Walsh M M, Tartter P I, Brower S T, Eng C M
Abstract excerpt
Based on breast cancer families with multiple and/or early-onset cases, estimates of the lifetime risk of breast cancer in carriers of BRCA1 or BRCA2 mutations may be as high as 85%. The risk for individuals not selected for family history or other risk factors is uncertain. We determined the fre...
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