Article
Mutations of the cationic trypsinogen in hereditary pancreatitis.
Human mutation - 1 Jan 1998
Teich N, Mössner J, Keim V
Abstract excerpt
Hereditary pancreatitis (OMIM 167800) is thought to be associated with a mutation of the exon 3 of cationic trypsinogen (Nature Genet (1996): 14:141-145). This paper reports sequence data of two independent families suffering from this disease. PCR amplificates from leukocyte or buccal swab DNA showed no mutation of exon 3 of cationic trypsinogen. Instead, in exon 2, an A-to-T tranversion was found that led to...
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