Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of the human mitochondrial aconitase gene (ACO2).

Gene - 15 Jun 1998

Mirel D B, Marder K, Graziano J, Freyer G, Zhao Q, Mayeux R, Wilhelmsen K C

Abstract excerpt

We have cloned and characterized the ACO2 gene on human chromosome 22q13, which encodes the essential iron-dependent metabolic enzyme mitochondrial aconitase. We determined that the ACO2 gene comprises 18 translated exons distributed over approximately 35 kilobasepairs (kbp) of DNA. We have shown...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cloning, Molecular

Share to DNA, Complementary

Share to Gene Expression Regulation

Share to Molecular Sequence Data

Source

Identifiers

PMID: 9630632
DOI: 10.1016/s0378-1119(98)00188-7

Genes

ACO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9630632-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Characterization of the human mitochondrial aconitase gene (ACO2).PMID 9630632Read ↗

Mitochondrial Aconitase and Its Contribution to the Pathogenesis of Neurodegenerative Diseases.Semantic proximity Read ↗

Expanding the clinical and phenotypic heterogeneity associated with biallelic variants in ACO2.Semantic proximity Read ↗

Infantile cerebellar-retinal degeneration associated with a mutation in mitochondrial aconitase, ACO2.Semantic proximity Read ↗

Mutations in the tricarboxylic acid cycle enzyme, aconitase 2, cause either isolated or syndromic optic neuropathy with encephalopathy and cerebellar atrophy.Semantic proximity Read ↗

Tissue-specific expression and chromosome assignment of genes specifying two isoforms of subunit VIIa of human cytochrome c oxidaseSemantic proximity Read ↗

Thr92Ala-DIO2 heterozygosity is associated with skeletal muscle mass and myosteatosis in patients with COVID-19.Semantic proximity Read ↗

The human Nramp2 gene: characterization of the gene structure, alternative splicing, promoter region and polymorphisms.Semantic proximity Read ↗

Mitochondrial Aconitase enzymatic activity: a potential long survival biomarker in the blood of ALS patientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.