Article
Comparative analysis of full-length genomic sequences of 10 dengue serotype 1 viruses associated with different genotypes, epidemics, and disease severity isolated in Thailand over 22 years.
The American journal of tropical medicine and hygiene - 1 Nov 2010
Tang Yuxin, Rodpradit Prinyada, Chinnawirotpisan Piyawan, Mammen Mammen P, Li Tao, Lynch Julia A, Putnak Robert, Zhang Chunlin
Abstract excerpt
Comparative sequence analysis was performed on the full-length genomic sequences of 10 representative dengue virus serotype 1 (DENV-1) strains sampled from patients at Children's Hospital, Bangkok, Thailand over a 22-year period, which represented different epidemics, disease severity, and sampling time. The results showed remarkable inter-genotypic variation between predominant and non-predominant genotypes and...
Topics
- Amino Acid Substitution
- Base Sequence
- Child
- Child, Preschool
- Dengue
- Dengue Virus
- Disease Outbreaks
- Female
- Genome, Viral
- Genotype
